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DHODH-IN-16
SKU
HY-139189-10 mg
Category Reference compound
Tags Cancer, Cell Cycle/DNA Damage;Metabolic Enzyme/Protease, Dihydroorotate Dehydrogenase;DNA/RNA Synthesis
$350 – $2,800
Products Details
Product Description
– DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 0.396 nM for human DHODH[1].
Web ID
– HY-139189
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C24H25FN4O3
References
– [1]Scott Kuduk, et al. Dihydroorotate dehydrogenase inhibitors. WO2020212897A1.
CAS Number
– 2511248-11-4
Molecular Weight
– 436.48
Compound Purity
– 99.88
SMILES
– O=C1C2=C(C(C(C)C)=CN1C3=C(C)C=CC=C3)C=C(N4N=C(CO)N(CC)C4=O)C(F)=C2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Dihydroorotate Dehydrogenase;DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.