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DGN549-L
8,142 CAD
Only 1000 item(s) left in stock.
Products Details
Product Description
– DGN549-L is a DNA alkylator that enables antibody conjugation at lysine residues, making it ideal for antibody-drug conjugate (ADC) synthesis.
Web ID
– T39316
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C58H58N8O13
References
– Bai C, et al. Site-Specific Conjugation of the Indolinobenzodiazepine DGN549 to Antibodies Affords Antibody-Drug Conjugates with an Improved Therapeutic Index as Compared with Lysine Conjugation. Bioconjug Chem. 2020;31(1):93-103.
CAS Number
– 1884276-68-9
Molecular Weight
– C58H58N8O13
SMILES
– [H][C@@]12Cc3ccccc3N1C(=O)c1cc(OC)c(OCc3cc(COc4cc5N=C[C@]6([H])Cc7ccccc7N6C(=O)c5cc4OC)cc(NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)CCCCC(=O)ON4C(=O)CCC4=O)c3)cc1NC2 |c:30|
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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