DGN462
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DGN462

SKU T11017-100 mg Category Brand:

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Products Details

Product Description

– DGN462 is an effective DNA alkylating agent with anti-tumor activity, as in acute myeloid leukemia (AML). DGN462 can be used as a cytotoxic component of antibody-drug conjugates (ADCs).

Web ID

– T11017

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C53H59N5O9S

References

– Hicks SW, et al. The novel CD19-targeting antibody-drug conjugate huB4-DGN462 shows improved anti-tumor activity compared to SAR3419 in CD19-positive lymphoma and leukemia models. Haematologica. 2019 Aug;104(8):1633-1639.

CAS Number

– 1394079-41-4

Molecular Weight

– C53H59N5O9S

SMILES

– O=C1N2C=3C(C[C@]2(CNC=4C1=CC(OC)=C(OCC5=CC(N(CCOCCOCCOC)CC(C)(C)S)=CC(COC6=C(OC)C=C7C(=C6)N=C[C@]8(N(C7=O)C=9C(C8)=CC=CC9)[H])=C5)C4)[H])=CC=CC3

Target

– ADC Linker

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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