Dextran sulfate sodium salt (MW 4500-5500)

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Products Details

Product Description

– Dextran sulfate sodium salt (MW 4500-5500) is a polymer of anhydroglucose with the molecular weight range of 4500-5500. Dextran sulfate sodium salt can be used to induce colitis. Dextran sulfate sodium salt also can inhibit the replication of the human immunodeficiency virus by preventing the adsorption of the virus into host cells[1][2][3].

Web ID

– HY-116282A

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– N/A

References

– [1]Baba M, et al. Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro. Proc Natl Acad Sci U S A. 1988 Aug;85(16):6132-6.|[2]Regmi S, et, al. Enhanced viability and function of mesenchymal stromal cell spheroids is mediated via autophagy induction. Autophagy. 2021 Oct;17(10):2991-3010.|[3]Araki Y, et, al. Dextran sulfate sodium administered orally is depolymerized in the stomach and induces cell cycle arrest plus apoptosis in the colon in early mouse colitis. Oncol Rep. 2012 Nov;28(5):1597-605.

CAS Number

– 9011-18-1

Molecular Weight

– 4500-5500

SMILES

– [Dextran sulfate sodium salt (MW 4500-5500)]

Clinical Information

– No Development Reported

Research Area

– Infection; Inflammation/Immunology

Solubility

– H2O : 100 mg/mL (ultrasonic)

Target

– Apoptosis;HIV

Pathway

– Anti-infection;Apoptosis

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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