Dexmedetomidine
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Dexmedetomidine

SKU T2524-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 62 CAD through 419 CAD

Products Details

Product Description

– Dexmedetomidine is a Central alpha-2 Adrenergic Agonist. The mechanism of action of dexmedetomidine is as an Adrenergic alpha2-Agonist. The physiologic effect of dexmedetomidine is by means of General Anesthesia.

Web ID

– T2524

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C13H16N2

Citations

– 1. Zhu Y X, Zhou J H, Li G W, et al. Dexmedetomidine protects liver cell line L-02 from oxygen-glucose deprivation-induced injury by down-regulation of microRNA-711. European Review for Medical and Pharmacological Sciences. 2018 Oct;22(19):6507-6516 2. Hou Z, Yang F, Chen K, et al.hUC-MSC-EV-miR-24 enhances the protective effect of dexmedetomidine preconditioning against myocardial ischemia–reperfusion injury through the KEAP1/Nrf2/HO-1 signaling.Drug Delivery and Translational Research.2023: 1-15. 3. Zhang Q, Huang Y, Gong C, et al.Dexmedetomidine attenuates inflammation and organ injury partially by upregulating Nur77 in sepsis.Immunity, Inflammation and Disease.2023, 11(6): e883. 4. Ren W, Chen J, Wang W, et al.Sympathetic nerve-enteroendocrine L cell communication modulates GLP-1 release, brain glucose utilization, and cognitive function.Neuron.2024

References

– Virtanen R, et al. Eur J Pharmacol, 1988, 150(1-2), 9-14.

CAS Number

– 113775-47-6

Molecular Weight

– C13H16N2

Compound Purity

– 0.9996

SMILES

– [C@H](C)(C1=C(C)C(C)=CC=C1)C2=CN=CN2

Pathway

– GPCR/G Protein|||Neuroscience

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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