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Detomidine
SKU
HY-B0163-10mg
Category Reference compound
Tags Adrenergic Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease; Endocrinology
Products Details
Product Description
– Detomidine, an imidazole derivative, is a potent α2-adrenergic agonist. Detomidine produces dose-dependent analgesic effects[1][2].
Web ID
– HY-B0163
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C12H14N2
References
– [1]J Still, et al. Cardiovascular and respiratory effects of detomidine in isoflurane-anaesthetised horses. J S Afr Vet Assoc. 1996 Dec;67(4):199-203.|[2]Virtanen R, et al. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic. J Vet Pharmacol Ther. 1985 Mar;8(1):30-7.
CAS Number
– 76631-46-4
Molecular Weight
– 186.25
SMILES
– CC1=C(C)C(CC2=CN=CN2)=CC=C1
Clinical Information
– Launched
Research Area
– Neurological Disease; Endocrinology
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.