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Desmethyl-VS-5584
Products Details
Product Description
– Desmethyl-VS-5584 is a dimethyl analog of VS-5584 which is an potent and selective mTOR/PI3K dual inhibitor with pyrido [2,3-d] pyrimidine structure[1].
Web ID
– HY-101776
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C16H20N8O
References
– [1]Hart S, Novotny-Diermayr V, Goh KC, et al. VS-5584, a novel and highly selective PI3K/mTOR kinase inhibitor for the treatment of cancer. Mol Cancer Ther. 2013;12(2):151-161.
CAS Number
– 1246535-95-4
Molecular Weight
– 340.38
SMILES
– NC1=NC=C(C2=C3N=CN(C(C)C)C3=NC(N4CCOCC4)=N2)C=N1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– mTOR;PI3K
Pathway
– PI3K/Akt/mTOR
Product type
– Reference compound
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