Desmethoxyyangonin
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Desmethoxyyangonin

SKU T5S0734-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 93 CAD through 2,512 CAD

Products Details

Product Description

– 1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydromethysticin and Desmethoxy yangonin involves transcription activation, probably through a PXR-independent or PXR-involved indirect mechanism.

Web ID

– T5S0734

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C14H12O3

References

– Ma Y , Sachdeva K , Liu J , et al. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23[J]. Drug Metabolism & Disposition the Biological Fate of Chemicals, 2004, 32(11):1317.

CAS Number

– 15345-89-8

Molecular Weight

– C14H12O3

Compound Purity

– 0.9961

SMILES

– COc1cc(C=Cc2ccccc2)oc(=O)c1

Pathway

– Neuroscience

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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