Dehydro Nifedipine

SKU T36665-1 mg Category Brand:

Price range: 67 CAD through 1,189 CAD

Products Details

Product Description

– Dehydro Nifedipine (BAY-b 4759) is the main metabolite of nifedipine in human plasma. Dehydro Nifedipine inhibits glucose uptake in PC-12 cells with an IC50 value of 130 μM. Nifedipine is a calcium channel blocker used in the treatment of hypertension and angina. Dehydronifedipine is formed when it is metabolized by cytochrome P450 (CYP) isomers CYP3A4 and CYP3A5.

Web ID

– T36665

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C17H16N2O6

References

– Shimada T, et al. Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver. Proc Natl Acad Sci U S A. 1989;86(2):462-465.

CAS Number

– 67035-22-7

Molecular Weight

– C17H16N2O6

Compound Purity

– 0.9865

SMILES

– COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c1ccccc1[N+]([O-])=O

Pathway

– Metabolism

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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