Deferoxamine
Add to CompareAdded to Compare

Download Files:

Deferoxamine

SKU T124358-1 mg Category Brand:

Price range: 102 CAD through 1,530 CAD

Products Details

Product Description

– Deferoxamine(Desferrioxamine B) is an iron chelator (binds Fe(III) and many other metal cations) that inhibits neuronopathy, may be used to modify the reduction of iron accumulation and deposition in tissues, and may improve neurological dysfunction by inhibiting ferroptosis and neuroinflammation following traumatic brain injury.Desferrioxamin-B has antioxidant, antiproliferative, Deferoxamine has antioxidant, antiproliferative, and antitumor activities, and can induce HIF-1α production, apoptosis and autophagy in cancer cells.Desferrioxamin-B can be used in the treatment of acute iron toxicity and COVID-19 related diseases.

Web ID

– T124358

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C25H48N6O8

Citations

– 1. Yong Y Y, Yan L, Wang B D, et al.Penthorum chinense Pursh inhibits ferroptosis in cellular and Caenorhabditis elegans models of Alzheimer’s disease.Phytomedicine.2024: 155463. 2. Bian Y, Shan G, Liang J, et al.Retinoic acid receptor alpha inhibits ferroptosis by promoting thioredoxin and protein phosphatase 1F in lung adenocarcinoma.Communications Biology.2024, 7(1): 1-13. 3. Chen H, Hu J, Xiong X, et al.SETD8 inhibits apoptosis and ferroptosis of Ewing’s sarcoma through YBX1/RAC3 axis.Cell Death & Disease.2024, 15(7): 494. 4. Bian Y, Shan G, Bi G, et al.Targeting ALDH1A1 to enhance the efficacy of KRAS-targeted therapy through ferroptosis.Redox Biology.2024: 103361.

References

– Duscher D, et al. Comparison of the Hydroxylase Inhibitor Dimethyloxalylglycine and the Iron Chelator Deferoxamine in Diabetic and Aged Wound Healing. Plast Reconstr Surg. 2017 Mar;139(3):695e-706e.

CAS Number

– 70-51-9

Molecular Weight

– C25H48N6O8

Compound Purity

– 0.9997

SMILES

– O=C(NCCCCCN(O)C(=O)C)CCC(=O)N(O)CCCCCNC(=O)CCC(=O)N(O)CCCCCN

Pathway

– Apoptosis|||Autophagy|||Angiogenesis|||Chromatin/Epigenetic|||Oxidation-Reduction

Product type

– Natural Product

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Related Products

Select options
Pseudotropine
Pseudotropine Price range: 46 CAD through 48 CAD
1 mL * 10 mM (in DMSO)200 mg

1000 in stock

Select options
Benzothiazolone
Benzothiazolone Price range: 48 CAD through 339 CAD
10 mg25 mg5 mg

1000 in stock

Select options
Oxindole
Oxindole Price range: 46 CAD through 59 CAD
1 mL * 10 mM (in DMSO)10 g5 g

1000 in stock

Select options
Lupinine
Lupinine Price range: 50 CAD through 296 CAD
1 mL * 10 mM (in DMSO)10 mg5 mg

1000 in stock

Select options
Tropinone
Tropinone Price range: 67 CAD through 74 CAD
1 mL * 10 mM (in DMSO)100 mg

1000 in stock

My Cart
Wishlist
Recently Viewed
Categories

Request Data Sheet / Safty Data Sheet

Please enable JavaScript in your browser to complete this form.
=

Price Request

Please enable JavaScript in your browser to complete this form.
=

Compare Products (0 Products)
document.addEventListener('elementor/popup/show', function() { if (typeof turnstile !== 'undefined') { document.querySelectorAll('.cf-turnstile').forEach(function(el) { if (!el.dataset.rendered) { turnstile.render(el); el.dataset.rendered = true; } }); } });