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Defactinib hydrochloride
Price range: 69 CAD through 250 CAD
Products Details
Product Description
– Defactinib hydrochloride (PF 04554878 hydrochloride) is a novel inhibitor of FAK. Which inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner.
Web ID
– T15092
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H22ClF3N8O3S
References
– Kang Y, et al. Role of focal adhesion kinase in regulating YB-1-mediated resistance in ovarian cancer. J Natl Cancer Inst. 2013 Oct 2;105(19):1485-95.
CAS Number
– 1073160-26-5
Molecular Weight
– C20H22ClF3N8O3S
Compound Purity
– 0.9878
SMILES
– Cl.CNC(=O)c1ccc(Nc2ncc(c(NCc3nccnc3N(C)S(C)(=O)=O)n2)C(F)(F)F)cc1
Target
– Others
Pathway
– Cytoskeletal Signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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