Debio 0932

SKU T15088-2 mg Category Brand:

102 CAD

Only 1000 item(s) left in stock.

Products Details

Product Description

– Debio 0932 (CUDC-305) is a heat shock protein 90 (Hsp90) inhibitor that targets the n-terminal atp-binding pocket to promote apoptosis, and has the advantage of being orally available and able to cross the blood-brain barrier (BBB) for the treatment of cancers such as non-small-cell lung cancer (NSCLC) and neuroblastoma.

Web ID

– T15088

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H30N6O2S

Citations

– 1. Lu X Y, Shi X J, Hu A, et al. Feeding induces cholesterol biosynthesis via the mTORC1–USP20–HMGCR axis. Nature. 2020, 588(7838): 479-484.

References

– Bao R, et al. CUDC-305, a novel synthetic HSP90 inhibitor with unique pharmacologic properties for cancer therapy. Clin Cancer Res. 2009 Jun 15;15(12):4046-57.

CAS Number

– 1061318-81-7

Molecular Weight

– C22H30N6O2S

Compound Purity

– 0.9898

SMILES

– N=1C=CC2=C(N=C(SC3=CC=4OCOC4C=C3N(C)C)N2CCNCC(C)(C)C)C1N

Target

– Apoptosis|||Topoisomerase

Pathway

– Metabolism|||Cytoskeletal Signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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