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Products Details
Product Description
– DDRI-18 is a novel small molecule inhibitor that regulates the DNA damage response with sensitizing and anticancer activities, inhibits non-homologous end-joining (NHEJ) DNA repair and enhances the cytotoxicity of anticancer DNA damage compounds.
Web ID
– T23974
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H20N6
References
– D W Jun, et al. Characterization of DDRI-18 (3,3′-(1H,3’H-5,5′-bibenzo[d]imidazole-2,2′-diyl)dianiline), a novel small molecule inhibitor modulating the DNA damage response. Br J Pharmacol. 2012 Sep;167(1):141-50.
CAS Number
– 4402-18-0
Molecular Weight
– C26H20N6
SMILES
– NC=1C=C(C=2NC=3C(N2)=CC=C(C3)C=4C=C5C(=CC4)N=C(N5)C6=CC(N)=CC=C6)C=CC1
Pathway
– DNA Damage/DNA Repair|||Cell Cycle/Checkpoint
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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