Download Files:
Products Details
Product Description
– DDRI-18 is a DNA damage response inhibitor that inhibits the non-homologous end-joining (NHEJ) DNA repair process. DDRI-18 is an effective chemosensitizing agent[1].
Web ID
– HY-123401
Shipping
– Room temperature
Molecular Formula
– C26H20N6
References
– [1]D W Jun, et al. Characterization of DDRI-18 (3,3′-(1H,3’H-5,5′-bibenzo[d]imidazole-2,2′-diyl)dianiline), a novel small molecule inhibitor modulating the DNA damage response. Br J Pharmacol. 2012 Sep;167(1):141-50.
CAS Number
– 4402-18-0
Molecular Weight
– 416.48
SMILES
– NC1=CC=CC(C2=NC3=CC=C(C=C3N2)C4=CC=C5N=C(NC5=C4)C6=CC(N)=CC=C6)=C1
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– DNA/RNA Synthesis
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
