Ddr1-In-1
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Ddr1-In-1

SKU T3337-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 56 CAD through 877 CAD

Products Details

Product Description

– DDR1-IN-1 is an effective and specific DDR1 receptor tyrosine kinase inhibitor (IC50: 105 nM), about 3-fold selectivity over DDR2.

Web ID

– T3337

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C30H31F3N4O3

Citations

– 1. Wang J, Xie S, Li N, et al. Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis. Bioactive Materials. 2022 2. Liu G, Jin X, Wang H, et al.Downregulation of CYRI-B promotes migration, invasion and EMT by activating the Rac1-STAT3 pathway in gastric cancer.Experimental Cell Research.2022: 113453.

References

– Kim HG, et al. ACS Chem Biol. 2013, 8(10), 2145-2150.

CAS Number

– 1449685-96-4

Molecular Weight

– C30H31F3N4O3

Compound Purity

– 0.9934

SMILES

– CCN1CCN(Cc2ccc(cc2C(F)(F)F)C(=O)Nc2ccc(C)c(Oc3ccc4NC(=O)Cc4c3)c2)CC1

Target

– Others

Pathway

– Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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