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DBCO-NHCO-PEG4-NH-Boc
$310 – $800
Products Details
Product Description
– DBCO-NHCO-PEG4-NH-Boc is a PEG/Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-NH-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Web ID
– HY-126884
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C34H45N3O8
References
– [1]Kuzmin A, et al. Surface functionalization using catalyst-free azide-alkyne cycloaddition.
CAS Number
– 1255942-12-1
Molecular Weight
– 623.74
Compound Purity
– 99.19
SMILES
– O=C(OC(C)(C)C)NCCOCCOCCOCCOCCC(NCCC(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Linker;PROTAC Linkers
Isoform
– Alkyl/ether Linkers;Cleavable Linker;PEG Linkers
Pathway
– Antibody-drug Conjugate/ADC Related;PROTAC
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
