Darovasertib
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Darovasertib

SKU T5600-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 77 CAD through 1,728 CAD

Products Details

Product Description

– Darovasertib (LXS196) is a potent, selective, and orally active protein kinase C (PKC) inhibitor with IC50 values of 1.9 nM for PKCα, 0.4 nM for PKCθ, and 3.1 μM for GSK3β.

Web ID

– T5600

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H23F3N8O

References

– Shoushtari A N , Shoushtari A N , Khan S , et al. A Phase Ib Study of Sotrastaurin, a PKC Inhibitor, and Alpelisib, a PI3Kα Inhibitor, in Patients with Metastatic Uveal Melanoma[J]. Cancers, 2021, 13(21):5504-.

CAS Number

– 1874276-76-2

Molecular Weight

– C22H23F3N8O

Compound Purity

– 0.9872

SMILES

– CC1(N)CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1C(F)(F)F

Pathway

– Chromatin/Epigenetic|||Cytoskeletal Signaling

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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