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Darglitazone
$110 – $180
Products Details
Product Description
– Darglitazone (CP-86325), a thiazolidinedione, is a potent, selective, and orally active PPAR-γ agonist. Darglitazone is effective in controlling blood glucose and lipid metabolism, and can be used for type II diabetes research[1].
Web ID
– HY-120160
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C23H20N2O4S
References
– [1]Rashmi Kumari, et al. The PPAR-gamma agonist, darglitazone, restores acute inflammatory responses to cerebral hypoxia-ischemia in the diabetic ob/ob mouse. J Cereb Blood Flow Metab. 2010 Feb;30(2):352-60.|[2]A Camirand, et al. Thiazolidinediones stimulate uncoupling protein-2 expression in cell lines representing white and brown adipose tissues and skeletal muscle. Endocrinology. 1998 Jan;139(1):428-31.
CAS Number
– 141200-24-0
Molecular Weight
– 420.48
Compound Purity
– 99.19
SMILES
– O=C1NC(SC1CC2=CC=C(C(CCC3=C(C)OC(C4=CC=CC=C4)=N3)=O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Metabolic Disease; Neurological Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– PPAR
Isoform
– PPARγ
Pathway
– Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
