Dapagliflozin-3-O-β-D-Glucuronide

SKU T35619-1 mg Category Small Compound Brand: TargetMol

Price range: 565 CAD through 1,069 CAD

Size

500 μg 1 mg

Clear

Products Details

Product Description

– Dapagliflozin-3-O-β-D-glucuronide is a metabolite of dapagliflozin . Dapagliflozin is a first generation selective sodium glucose cotransporter (SGLT) 2 inhibitor that blocks glucose transport.[1] Dapagliflozin is metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A9 to dapagliflozin-3-O-β-D-glucuronide, which is 2,600-fold less potent than the parent compound with regard to SGLT2 inhibition.[2]

Web ID

– T35619

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C27H33ClO12

References

– Chao, E.C., and Henry, R.R. SGLT2 inhibition – A novel strategy for diabetes treatment. Nature Reviews.Drug Discovery 9(7), 551-559 (2010).

CAS Number

– 1351438-75-9

Molecular Weight

– C27H33ClO12

SMILES

– O[C@H]1[C@@H](O[C@H](CO)[C@@H](O)[C@@H]1O[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O)C3=CC(CC4=CC=C(OCC)C=C4)=C(Cl)C=C3

Target

– Gamma-secretase

Pathway

– Others

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.