D3-βArr

SKU T5383-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 50 CAD through 698 CAD

Products Details

Product Description

– D3-βArr (NCGC00379308) is a positive allosteric modulator for thyrotropin receptor (TSHR), which initiates translocation of β-Arr 1 (EC50: 11.6 μM) by direct TSHR activation.

Web ID

– T5383

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H23N5

References

– Neumann S, et al. Discovery of a Positive Allosteric Modulator of the Thyrotropin Receptor: Potentiation of Thyrotropin-Mediated Preosteoblast Differentiation In Vitro. J Pharmacol Exp Ther. 2018 Jan;364(1):38-45.

CAS Number

– 662164-09-2

Molecular Weight

– C20H23N5

Compound Purity

– 0.9882

SMILES

– CC(Nc1nc(nc2ccccc12)N1CCNCC1)c1ccccc1

Pathway

– GPCR/G Protein

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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