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Products Details
Product Description
– PD-1/PD-L1 interaction inhibitor. Binds to PD-L1 (Kd = 0.51 μM). Inhibits interaction at 1 mg/mL in flow cytometry. Inhibits tumor growth and prolongs survival time of mice in vivo.
Web ID
– TP1960
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C70H98N20O21
References
– Chang et al (2015) Blocking of the PD-1/PD-L1 interaction by a D-peptide antagonist for cancer immunotherapy. Angew Chem.Int.Ed.Engl. 54 11760 PMID:
CAS Number
– 1620813-53-7
Molecular Weight
– C70H98N20O21
SMILES
– C([C@H](NC([C@H](NC([C@@H](CC1=CC=C(O)C=C1)NC([C@@H](CC(N)=O)N)=O)=O)CO)=O)CCCCN)(=O)N2[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@@H](C(N[C@H](CC3=CC=C(O)C=C3)C(N[C@H](CC4=CN=CN4)C(N[C@H](CC5=CC=CC=C5)C(O)=O)=O)=O)=O)CCC(N)=O)=O)CCCNC(=N)N)=O)CC(O)=O)=O)[C@H](C)O)=O)CCC2
Product type
– Peptide
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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