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Product Description
– N(G)-Nitro-D-arginine methyl ester (D-NAME) is the less active enantiomer of the nitric oxide (NO) synthase inhibitor N(G)-nitro-L-arginine methyl ester . D-NAME was initially thought to be inactive and was often used as a negative control for L-NAME. Later studies showed that D-NAME (40 mg/kg/day in rats) can have similar but less pronounced effects as L-NAME (40 mg/kg/day in rats) in the cardiovascular system, particularly at long-term timepoints. D-NAME (3-10 µg/mouse) had no effect on nociception in mice assessed using the tail flick test.
Web ID
– T36719
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C7H16ClN5O4
References
– Palmer, R.M.J., Rees, D.D., Ashton, D.S., et al. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation Biochem. Biophys. Res. Commun. 153(3), 1251-1256 (1988).
CAS Number
– 50912-92-0
Molecular Weight
– C7H16ClN5O4
SMILES
– COC(=O)[C@H](N)CCCNC(=N)N[N+]([O-])=O
Pathway
– Others
Product type
– Small Compound
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