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Products Details
Product Description
– D-MoDE-A (1) is a bifunctional small molecule that mediates the degradation of extracellular proteins through the asialoglycoprotein receptor (ASGPR).
Web ID
– HY-142881
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C71H121N11O39
References
– [1]Caianiello DF, et al. Bifunctional small molecules that mediate the degradation of extracellular proteins. Nat Chem Biol. 2021 Sep;17(9):947-953.
CAS Number
– 2378837-67-1
Molecular Weight
– 1752.77
SMILES
– O=[N+]([O-])C(C=C(C=C1)[N+]([O-])=O)=C1NCCOCCOCCOCC(NCC(NC(COCCC(NCCOCCOCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)NC(C)=O)=O)(COCCC(NCCOCCOCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)CO)O)O)NC(C)=O)=O)COCCC(NCCOCCOCCO[C@H]4[C@@H]([C@H]([C@H]([C@H](O4)CO)O)O)NC(C)=O)=O)=O)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– 10 mM in DMSO
Target
– LYTACs
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
