[D-Arg1
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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate

SKU TP1931L1-1 mg Category Brand:

Price range: 229 CAD through 4,784 CAD

Products Details

Product Description

– [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist for the ghrelin receptor (EC50 = 5.2 nM); diminishes constitutive ghrelin receptor signaling. Also antagonist at tachykinin, bradykinin, CCK and bombesin receptors. Induces apoptosis and inhibits cancer cell growth in vitro.

Web ID

– TP1931L1

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C81H113N19O14

References

– Holst et al (2003) High constitutive signaling of the ghrelin receptor – identification of a potent inverse agonist. Mol.Endocrinol. 17 2201 PMID:

Molecular Weight

– C81H113N19O14

Compound Purity

– 0.9768

SMILES

– CC(C)C[C@@H](C(N)=O)NC([C@H](CC(C)C)NC([C@@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=CC=C3)NC([C@@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CCC(N)=O)NC([C@@H](CC6=CC=CC=C6)NC([C@H]7N(C([C@H](CCCCN)NC([C@H]8N(C([C@@H](CCCNC(N)=N)N)=O)CCC8)=O)=O)CCC7)=O)=O)=O)=O)=O)=O)=O.CC(O)=O

Pathway

– GPCR/G Protein

Product type

– Peptide

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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