CZC-54252 hydrochloride
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CZC-54252 hydrochloride

SKU T39202-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 70 CAD through 757 CAD

Products Details

Product Description

– CZC-54252 hydrochloride is a selective inhibitor of LRRK2 with IC50s of 1.85 nM and 1.28 nM for wild-type and G2019S LRRK2. CZC-54252 hydrochloride has a neuroprotective activity and attenuates G2019S LRRK2-induced human neuronal injury with an EC50 of 1 nM.

Web ID

– T39202

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H26Cl2N6O4S

References

– Nigel Ramsden, et al. Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson’s disease-related toxicity in human neurons. ACS Chem Biol. 2011 Oct 21;6(10):1021-8.

CAS Number

– 1784253-05-9

Molecular Weight

– C22H26Cl2N6O4S

Compound Purity

– 0.9821

SMILES

– Cl.COc1cc(ccc1Nc1ncc(Cl)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1

Pathway

– Autophagy

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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