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Product Description
– Cytochalasin H is a nature product that could be isolated from fungus Phomopsis sp. Cytochalasin H inhibits cell growth and induces apoptosis. Cytochalasin H has anti-angiogenic activity. Cytochalasin H is an antibiotic and has antibacterial activity[1][2][3].
Web ID
– HY-129325
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C30H39NO5
References
– [1]Ma Y, et, al. Cytochalasin H isolated from mangrove‑derived endophytic fungus induces apoptosis and inhibits migration in lung cancer cells. Oncol Rep. 2018 Jun;39(6):2899-2905.|[2]Yi JM, et, al. In Vivo Anti-tumor Effects of the Ethanol Extract of Gleditsia sinensis Thorns and Its Active Constituent, Cytochalasin H. Biol Pharm Bull. 2015;38(6):909-12.|[3]Jouda JB, et, al. Antibacterial and cytotoxic cytochalasins from the endophytic fungus Phomopsis sp. harbored in Garcinia kola (Heckel) nut. BMC Complement Altern Med. 2016 Nov 14;16(1):462.
CAS Number
– 53760-19-3
Molecular Weight
– 493.63
SMILES
– O=C([C@@]12[C@](/C=C/C[C@H](C)C[C@@](C)(O)/C=C/[C@H]2OC(C)=O)([H])[C@@H]3O)N[C@@H](CC4=CC=CC=C4)[C@]1([H])[C@H](C)C3=C
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Apoptosis;Bacterial;Bcl-2 Family;Caspase
Pathway
– Anti-infection;Apoptosis
Product type
– Natural Products
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