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Cyprodinil
SKU
HY-116214-10mM/1mL
Category Reference compound
Tags Androgen Receptor;Fungal, Anti-infection;Vitamin D Related/Nuclear Receptor, Infection; Endocrinology
$50 – $55
Products Details
Product Description
– Cyprodinil is an anilinopyrimidine broad-spectrum fungicide that inhibits the biosynthesis of methionine in phytopathogenic fungi. Cyprodinil inhibits mycelial cell growth of B. cinerea, P. herpotrichoides, and H. oryzae on amino acid-free media (IC50s=0.44, 4.8, and 0.03 µM, respectively). Cyprodinil acts as an androgen receptor (AR) agonist (EC50=1.91 µM) in the absence of the AR agonist DHT and inhibits the androgenic effect of DHT (IC50=15.1 µM).
Web ID
– HY-116214
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H15N3
References
– [1]Masner, P., et al. Possible methionine biosynthesis inhibition by pyrimidinamine fungicides. Pestic. Sci. 42(3),163-166 (1994).|[2]Frances Orton, et al. Widely used pesticides with previously unknown endocrine activity revealed as in vitro antiandrogens. Environ Health Perspect. 2011 Jun;119(6):794-800.
CAS Number
– 121552-61-2
Molecular Weight
– 225.29
Compound Purity
– 99.36
SMILES
– CC1=CC(C2CC2)=NC(NC3=CC=CC=C3)=N1
Clinical Information
– No Development Reported
Research Area
– Infection; Endocrinology
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Androgen Receptor;Fungal
Pathway
– Anti-infection;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
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