Download Files:
CYP1B1-IN-4
$70 – $350
Products Details
Product Description
– CYP1B1-IN-4 is a 2,4-diarylthiazole compound with selectively CYP1B1 inhibition (IC50=0.2 nM). CYP1B1-IN-4 has little cytotoxicity and high stability in both human and rat liver microsomes[1].
Web ID
– HY-152118
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C18H14N2O2S
References
– [1]Hachey AC, et al. Design of Cytochrome P450 1B1 Inhibitors via a Scaffold-Hopping Approach. J Med Chem. 2022 Dec 15.
CAS Number
– 2685779-55-7
Molecular Weight
– 322.38
Compound Purity
– 99.09
SMILES
– COC1=CC=C(C(OC)=C1)C2=NC(C3=CC=C(C=C3)C#N)=CS2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 62.5 mg/mL (ultrasonic)
Target
– Cytochrome P450
Isoform
– CYP1
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
