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Products Details
Product Description
– Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with an IC50 of 20 nM.
Web ID
– HY-100563A
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C27H41N9O8
Citations
– Biochem Pharmacol. 2023 Sep 14;115808.|Pharmaceuticals. 2021 Mar 14;14(3):260.|Stem Cell Res Ther. 2022 Jul 18;13(1):327.
References
– [1]Haubner R, et al. Glycosylated RGD-containing peptides: tracer for tumor targeting and angiogenesis imaging with improved biokinetics. J Nucl Med. 2001 Feb;42(2):326-36.
CAS Number
– 217099-14-4
Molecular Weight
– 619.67
SMILES
– OC(C=C1)=CC=C1C[C@@H](N2)C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CC(O)=O)C2=O)=O)=O)CCCNC(N)=N)=O)CCCCN)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Integrin
Isoform
– αvβ3
Pathway
– Cytoskeleton
Product type
– Peptides
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
