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Cyclopropaneacetamide-Exatecan
SKU
HY-156617-Get quote
Category ADC Related
Tags ADC Cytotoxin, Antibody-drug Conjugate/ADC Related, Cancer
Products Details
Product Description
– Cyclopropaneacetamide-Exatecan (Compound 2-A) is an ADC Cytotoxin and an Exatecan analogue. Cyclopropaneacetamide-Exatecan can be used in the synthesis of ADC such as anti-B7H3 antibody-Exatecan analogue conjugate (compound ADC-2)[1].
Web ID
– HY-156617
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H28FN3O6
References
– [1]Ying Hua, et al. Anti-b7h3 antibody-exatecan analog conjugate and medicinal use thereof. Patent WO2020063673A1.
CAS Number
– 2414254-36-5
Molecular Weight
– 533.55
SMILES
– O[C@@H](C1CC1)C(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– ADC Cytotoxin
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.