Products Details

Product Description

– CXCR4 antagonist 7 (Compound PARA-B) is a CXCR4 antagonist with the IC50 of 9.3 nM. CXCR4 antagonist 7 can be used for the research of HIV infection, inflammatory diseases, cancer, and WHIM syndrome[1].

Web ID

– HY-147808

Shipping

– Room temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C15H17N5O3

References

– [1]Rosa Maria Vitale, et al. Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization. Bioorg Chem. 2020 Dec;105:104337.

CAS Number

– 1185451-72-2

Molecular Weight

– 315.33

SMILES

– O=C(N(C(N/1)=O)/C=C/C2=CC=C(O)C=C2)C1=CCC/N=C(N)/N

Clinical Information

– No Development Reported

Research Area

– Infection; Cancer; Inflammation/Immunology

Solubility

– 10 mM in DMSO

Target

– CXCR;HIV

Isoform

– CXCR4

Pathway

– Anti-infection;GPCR/G Protein;Immunology/Inflammation

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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