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Products Details
Product Description
– CXCR4 antagonist 7 (Compound PARA-B) is a CXCR4 antagonist with the IC50 of 9.3 nM. CXCR4 antagonist 7 can be used for the research of HIV infection, inflammatory diseases, cancer, and WHIM syndrome[1].
Web ID
– HY-147808
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C15H17N5O3
References
– [1]Rosa Maria Vitale, et al. Identification of the hydantoin alkaloids parazoanthines as novel CXCR4 antagonists by computational and in vitro functional characterization. Bioorg Chem. 2020 Dec;105:104337.
CAS Number
– 1185451-72-2
Molecular Weight
– 315.33
SMILES
– O=C(N(C(N/1)=O)/C=C/C2=CC=C(O)C=C2)C1=CCC/N=C(N)/N
Clinical Information
– No Development Reported
Research Area
– Infection; Cancer; Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– CXCR;HIV
Isoform
– CXCR4
Pathway
– Anti-infection;GPCR/G Protein;Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
