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Products Details
Product Description
– CUDC-427 is a potent second-generation pan-selective IAP antagonist, used for treatment of various cancers.
Web ID
– HY-15835
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C29H36N6O4S
References
– [1]Wong H, et al. Learning and confirming with preclinical studies: modeling and simulation in the discovery of GDC-0917, an inhibitor of apoptosis proteins antagonist. Drug Metab Dispos. 2013 Dec;41(12):2104-13.
CAS Number
– 1446182-94-0
Molecular Weight
– 564.70
Compound Purity
– 99.01
SMILES
– O=C([C@H](CCC1)N1C([C@H](C2CCCCC2)NC([C@H](C)NC)=O)=O)NC3=C(C4=CC=CC=C4)N=C(C5=NC=CO5)S3
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– IAP
Pathway
– Apoptosis
Product type
– Reference compound
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