CRT0066854 hydrochloride

SKU T10888-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 90 CAD through 1,142 CAD

Products Details

Product Description

– CRT0066854 hydrochloride is an effective selective atypical PKCs inhibitor. CRT0066854 is against full-length (FL) PKCι, PKCζ, and ROCK-II kinases with IC50 values of 132 nM, 639 nM, and 620 nM, respectively.

Web ID

– T10888

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H27Cl2N5S

References

– Kjær S, et al. Adenosine-binding motif mimicry and cellular effects of a thieno[2,3-d]pyrimidine-based chemical inhibitor of atypical protein kinase C isoenzymes. Biochem J. 2013 Apr 15;451(2):329-42.

CAS Number

– 2250019-91-9

Molecular Weight

– C24H27Cl2N5S

Compound Purity

– 0.9751

SMILES

– N[C@@H](CC1=CC=CC=C1)CNC2=C3C4=C(CCCC4)SC3=NC(C5=CC=NC=C5)=N2.Cl.Cl

Target

– PAFR

Pathway

– Cytoskeletal Signaling|||Cell Cycle/Checkpoint|||Chromatin/Epigenetic|||Stem Cells

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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