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Cromakalim
SKU
HY-110011-10 mg
Category Reference compound
Tags Inflammation/Immunology, Membrane Transporter/Ion Channel, Potassium Channel
$68 – $680
Products Details
Product Description
– Cromakalim is a potassium channel opener. Cromakalim can be used as a bronchodilator in asthma. Cromakalim inhibits the spontaneous tone of human isolated bronchi in a concentration-related manner being nearly as effective as isoprenaline or theophylline[1].
Web ID
– HY-110011
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C16H18N2O3
References
– [1]Cortijo J, et al. The relaxant effects of cromakalim (BRL 34915) on human isolated airway smooth muscle. Naunyn Schmiedebergs Arch Pharmacol. 1992;346(4):462-468.
CAS Number
– 94470-67-4
Molecular Weight
– 286.33
Compound Purity
– 99.39
SMILES
– O[C@@H]1[C@@H](N2C(CCC2)=O)C3=CC(C#N)=CC=C3OC1(C)C
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 66.67 mg/mL (ultrasonic)
Target
– Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.