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cRIPGBM chloride
Price range: 48 CAD through 942 CAD
Products Details
Product Description
– cRIPGBM chloride is an apoptosis-promoting derivative present in GBM cancer stem cells with antitumor activity. It induces caspase-1 dependent cell apoptosis by interacting with receptor-interacting protein kinase 2 (RIPK2) and acting as a molecular switch. cRIPGBM chloride reduces the formation of pro-survival RIPK2/TAK1 complexes and increases the formation of pro-apoptotic RIPK2/caspase 1 complexes, which can be used to study brain tumors.
Web ID
– T72658
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H20ClFN2O2
CAS Number
– 2361988-77-2
Molecular Weight
– C26H20ClFN2O2
Compound Purity
– 0.9975
SMILES
– [Cl-].O=C1C=2C=CC=CC2C(=O)C3=C1N(C(=[N+]3CC4=CC=C(F)C=C4)C)CC=5C=CC=CC5
Pathway
– NF-κB|||Proteases/Proteasome|||Apoptosis
Product type
– Small Compound
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