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Products Details
Product Description
– COX-2-IN-33 (compound 5f) is a COX-2 inhibitor (IC50=45.5 nM), as well as a potential anti-inflammatory agent. COX-2-IN-33 inhibits in vivo pro-inflammatory cytokine production and keep gastric safety[1].
Web ID
– HY-149355
Shipping
– Room temperature
Molecular Formula
– C20H13ClF3N5O4
References
– [1]Li SM, et al. Synthesis and anti-inflammatory activity evaluation of NO-releasing furoxan/1,2,4-triazole hybrid derivatives. Eur J Med Chem. 2023 Sep 5;257:115496.
Molecular Weight
– 479.80
SMILES
– O=C(OCC1=[N+]([O-])ON=C1C2=CC=CC=C2)C3=NN(C4=CC=CC(C(F)(F)F)=C4)C(CCl)=N3
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– COX
Pathway
– Immunology/Inflammation
Product type
– Reference compound
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