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Cordycepin
$35 – $335
Products Details
Product Description
– Cordycepin (3′-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner[1]. Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase[2].
Web ID
– HY-N0262
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-Kinase/protease
Molecular Formula
– C10H13N5O3
References
– [1]Noh EM, et al. Cordycepin inhibits IL-1beta-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts. Rheumatology (Oxford). 2009 Jan;48(1):45-8.|[2]Huang F, et al. Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase. PLoS One. 2019 Jun 14;14(6):e0218449.
CAS Number
– 73-03-0
Molecular Weight
– 251.24
Compound Purity
– 99.0
SMILES
– OC[C@@H]1C[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O1
Clinical Information
– Phase 2
Research Area
– Cancer; Infection; Inflammation/Immunology
Solubility
– DMSO : 33.33 mg/mL (ultrasonic)|H2O : 2 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Antibiotic;Autophagy;Bacterial;MMP
Isoform
– MMP-1;MMP-3
Pathway
– Anti-infection;Autophagy;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
