Conteltinib
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Conteltinib

SKU T14997-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 112 CAD through 1,349 CAD

Products Details

Product Description

– Conteltinib (CT-707) is an enzyme inhibitor with antitumor activity targeting FAK, ALK, and Pyk2.Conteltinib exhibits significant inhibition of FAK, overcomes hypoxia-mediated sorafenib resistance in hepatocellular carcinoma through inhibition of YAP signaling, and can be used in advanced ALK-positive non-small-cell lung cancer and lymphoma.

Web ID

– T14997

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C32H45N9O3S

References

– Wang DD, et al. CT-707, a Novel FAK Inhibitor, Synergizes with Cabozantinib to Suppress Hepatocellular Carcinoma by Blocking Cabozantinib-Induced FAK Activation. Mol Cancer Ther. 2016 Dec;15(12):2916-2925.

CAS Number

– 1384860-29-0

Molecular Weight

– C32H45N9O3S

Compound Purity

– 0.9954

SMILES

– COc1cc(ccc1Nc1nc2NCCc2c(Nc2ccccc2S(=O)(=O)NC(C)C)n1)N1CCC(CC1)N1CCN(C)CC1

Target

– Others

Pathway

– Cytoskeletal Signaling|||Angiogenesis|||Tyrosine Kinase/Adaptors

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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