Concizumab

SKU T77373-1 mg Category Brand:

Price range: 365 CAD through 3,088 CAD

Products Details

Product Description

– Concizumab is an anti-TFPI monoclonal antibody (IgG4 type) that selectively binds to the Kunitz protease inhibitor (KPI) 2 domain of TFPI, blocking its interaction with the FXa active site. Injections of Concizumab increase thrombin in blood, thereby preventing and treating hemophilia.

Web ID

– T77373

Storage Temperature

– -20℃

Shipping

– Blue Ice

References

– Kjalke M, et al. Thrombin generation potential in the presence of concizumab and rFVIIa, APCC, rFVIII, or rFIX: In vitro and ex vivo analyses. J Thromb Haemost. 2021 Jul;19(7):1687-1696.

CAS Number

– 1312299-39-0

Molecular Weight

Compound Purity

– > 95%

Pathway

– Others

Product type

– Inhibitory Antibodies

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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