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Products Details
Product Description
– ConB-1 is a potent and selective ALK inhibitor with low toxicity to normal cells[1].
Web ID
– HY-142287
Shipping
– Room temperature
Applications
– Cancer-Kinase/protease
Molecular Formula
– C38H52ClN7O6S
References
– [1]Yan G, et al. Targeting Cysteine Located Outside the Active Site: An Effective Strategy for Covalent ALKi Design. J Med Chem. 2021 Feb 11;64(3):1558-1569.
CAS Number
– 2415537-51-6
Molecular Weight
– 770.38
SMILES
– C=CC(NCCOCCNC(CCN1CCC(CC1)C2=CC(OC(C)C)=C(C=C2C)NC3=NC(NC4=C(C=CC=C4)S(=O)(C(C)C)=O)=C(C=N3)Cl)=O)=O
Clinical Information
– Phase 1
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Anaplastic lymphoma kinase (ALK)
Pathway
– Protein Tyrosine Kinase/RTK
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
