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Cloxiquine
$50 – $60
Products Details
Product Description
– Cloxiquine (5-Chloro-8-quinolinol) is an antibacterial, antifungal and antiamoebic agent. Cloxiquine can be used for the research of tuberculosis and dermatoses. Cloxiquine suppresses the growth and metastasis of melanoma cells through activation of PPARγ[1][2].
Web ID
– HY-B0963
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C9H6ClNO
References
– [1]LatosiÅ„ska JN, et al. Supramolecular synthon pattern in solid clioquinol and cloxiquine (APIs of antibacterial, antifungal, antiaging and antituberculosis drugs) studied by <sup>35</sup>Cl NQR, <sup>1</sup>H-<sup>17</sup>O and <sup>1</sup>H-<sup>14</sup>N NQDR and DFT/QTAIM. J Mol Model. 2011 Jul;17(7):1781-800.|[2]Hongmanee P, et, al. In vitro activities of cloxyquin (5-chloroquinolin-8-ol) against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2007 Mar;51(3):1105-6.|[3]Zhang W, et, al. Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPARγ. Cell Death Dis. 2019 May 28;10(6):404.
CAS Number
– 130-16-5
Molecular Weight
– 179.60
Compound Purity
– 99.66
SMILES
– OC1=C2N=CC=CC2=C(Cl)C=C1
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Bacterial;Fungal;Parasite;PPAR
Isoform
– Amebae
Pathway
– Anti-infection;Cell Cycle/DNA Damage;Vitamin D Related/Nuclear Receptor
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
