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CLK1-IN-2
$130 – $1,100
Products Details
Product Description
– CLK1-IN-2 is metabolically stable Clk1 inhibitor. CLK1-IN-2 has selectivity for Clk1 with an IC50 value of 1.7 nM. CLK1-IN-2 can be used for the research of tumour, Duchenne’s muscular dystrophy and viral infections such as HIV-1 and influenza[1].
Web ID
– HY-152219
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C16H12Cl2N2O2S
References
– [1]Dalia S El-Gamil, et al. Discovery of novel 5-methoxybenzothiophene hydrazides as metabolically stable Clk1 inhibitors with high potency and unprecedented Clk1 isoenzyme selectivity. Eur J Med Chem. 2022 Dec 15;247:115019.
Molecular Weight
– 367.25
Compound Purity
– 98.73
SMILES
– O=C(C1=CC2=CC(OC)=CC=C2S1)NNC3=CC(Cl)=CC(Cl)=C3
Clinical Information
– No Development Reported
Research Area
– Cancer; Infection
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– CDK
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
