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Product Description
– Clemastine (HS-592) is a potent and orally active histamine receptor H1 antagonist. Clemastine is an antihistamine mainly used for relieving symptoms of allergic reactions primarily by competing with histamine to bind H1 receptors. Anti-inflammatory effects[1][2].
Web ID
– HY-B0298
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C21H26ClNO
Citations
– Methods Mol Biol. 2023;2683:103-111.|Biochem Biophys Res Commun. 2020 Feb 19;522(4):862-868.|Cell Prolif. 2021 Jan;54(1):e12953.|Microbiol Spectr. 2022 Mar 2;e0054121.|Prog Neuropsychopharmacol Biol Psychiatry. 2023 Nov 28:110901.|Viruses. 2021 Jun 28;13(7):1255.
References
– [1]Clemastine. In: LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; January 16, 2017.
CAS Number
– 15686-51-8
Molecular Weight
– 343.89
SMILES
– CN1[C@@H](CCO[C@](C2=CC=CC=C2)(C3=CC=C(Cl)C=C3)C)CCC1
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Isoform
– H1 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
