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Products Details
Product Description
– Clathrin-IN-1 is a selective clathrin-mediated endocytosis (CME) inhibitor. Clathrin-IN-1 selectively inhibits amphiphysin association of clathrin terminal domain (TD) with an IC50 value of 12 μM. Clathrin-IN-1 acutely interferes with receptor-mediated endocytosis, entry of HIV, and synaptic vesicle recycling[1].
Web ID
– HY-102068
Shipping
– Room temperature
Applications
– COVID-19-anti-virus
Molecular Formula
– C20H13BrN2O3S2
References
– [1]Lisa von Kleist, et al. Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell. 2011 Aug 5;146(3):471-84.
CAS Number
– 1332879-52-3
Molecular Weight
– 473.36
SMILES
– O=S(C1=C2C=CC=CC2=CC=C1)(NC(S/C3=CC4=CC=C(Br)C=C4)=NC3=O)=O
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– HIV
Isoform
– HIV-1
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
