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Products Details
Product Description
– Cinchonine ((8R,9S)-Cinchonine) monohydrochloride hydrate is a natural compound which has been effectively used as antimalarial agent. Cinchonine monohydrochloride hydrate activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Cinchonine monohydrochloride hydrate is also an inhibitor of human platelet aggregation. Cinchonine monohydrochloride hydrate possesses a suppressive effect on adipogenesis[1].
Web ID
– HY-Y0152A
Shipping
– Room temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C19H22N2O.HCl.xH2O
References
– [1]Jin ZL, et, al. Cinchonine activates endoplasmic reticulum stress-induced apoptosis in human liver cancer cells. Exp Ther Med. 2018 Jun;15(6):5046-5050.
CAS Number
– 206986-88-1
Molecular Weight
– N/A
SMILES
– O[C@@H](C1=CC=NC2=CC=CC=C12)[C@]3([H])[N@@]4C[C@H](C=C)[C@@H](CC4)C3.[H]Cl.[x].O
Clinical Information
– No Development Reported
Research Area
– Cancer, Infection, Metabolic Disease, Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Apoptosis, Parasite
Isoform
– Plasmodium
Pathway
– Anti-infection, Apoptosis
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
