Cilostamide

$77$803

Products Details

Product Description

– Cilostamide is a selective and potent PDE3 inhibitor, with IC50s of 27 nM and 50 nM for PDE3A and PDE3B, respectively, and has antithrombotic and anti-intimal hyperplastic activity.

Web ID

– HY-101312

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C20H26N2O3

References

– [1]Sudo T, et al. Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity. Biochem Pharmacol. 2000 Feb 15;59(4):347-56.

CAS Number

– 68550-75-4

Molecular Weight

– 342.43

Compound Purity

– 99.64

SMILES

– O=C(N(C1CCCCC1)C)CCCOC2=CC3=C(NC(C=C3)=O)C=C2

Clinical Information

– No Development Reported

Research Area

– Cardiovascular Disease

Solubility

– DMSO : 31 mg/mL (ultrasonic;warming)

Target

– Phosphodiesterase (PDE)

Isoform

– PDE3

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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