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Cilostamide
SKU
HY-101312-10 mg
Category Reference compound
Tags Cardiovascular Disease, Metabolic Enzyme/Protease, Phosphodiesterase (PDE)
$77 – $803
Products Details
Product Description
– Cilostamide is a selective and potent PDE3 inhibitor, with IC50s of 27 nM and 50 nM for PDE3A and PDE3B, respectively, and has antithrombotic and anti-intimal hyperplastic activity.
Web ID
– HY-101312
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C20H26N2O3
References
– [1]Sudo T, et al. Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity. Biochem Pharmacol. 2000 Feb 15;59(4):347-56.
CAS Number
– 68550-75-4
Molecular Weight
– 342.43
Compound Purity
– 99.64
SMILES
– O=C(N(C1CCCCC1)C)CCCOC2=CC3=C(NC(C=C3)=O)C=C2
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 31 mg/mL (ultrasonic;warming)
Target
– Phosphodiesterase (PDE)
Isoform
– PDE3
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.