Download Files:
Products Details
Product Description
– cIAP1 Ligand-Linker Conjugates 5 incorporates an IAP ligand for the E3 ubiquitin ligase, and a PROTAC linker. cIAP1 Ligand-Linker Conjugates 5 can be used to design SNIPERs[1].
Web ID
– HY-128818
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C37H55N5O8S
References
– [1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
CAS Number
– 2113688-20-1
Molecular Weight
– 729.93
SMILES
– C[C@H](N(C(OC(C)(C)C)=O)C)C(N[C@@H](C1CCCCC1)C(N(CCC2)[C@@H]2C3=NC(C(C4=CC=CC(OCCOCCOCCN)=C4)=O)=CS3)=O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– cIAP1
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
