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Chromanol 293B
$270 – $430
Products Details
Product Description
– Chromanol 293B is a selective blocker of the slow delayed rectifier K+ current (IKs) with IC50 of 1-10 μM and a weak inhibitor of KATP channel. Chromanol 293B also blocks the CFTR chloride current with an IC50 of 19 μM[1].
Web ID
– HY-108575
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C15H20N2O4S
References
– [1]Bachmann A, Quast U, Russ U. Chromanol 293B, a blocker of the slow delayed rectifier K+ current (IKs), inhibits the CFTR Cl- current. Naunyn Schmiedebergs Arch Pharmacol. 2001 Jun;363(6):590-6.
CAS Number
– 163163-23-3
Molecular Weight
– 324.40
Compound Purity
– 98.0
SMILES
– CCS(N([C@H]1C2=CC(C#N)=CC=C2OC(C)([C@@H]1O)C)C)(=O)=O
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMF : ≥ 30 mg/mL|DMSO : ≥ 30 mg/mL|Ethanol : ≥ 2 mg/mL
Target
– CFTR;Potassium Channel
Pathway
– Membrane Transporter/Ion Channel
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
