Download Files:
Chlorpyrifos
$55 – $75
Products Details
Product Description
– Chlorpyrifos is a neurotoxic insecticide that belongs to the class of thionite esters. Chlorpyrifos is also a AChE inhibitor that affects neurological function in insects, humans and other animals. Chlorpyrifos interferes with cell replication and differentiation, ultimately altering synaptic transmission in neurons[1][2][3][4].
Web ID
– HY-B0815
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C9H11Cl3NO3PS
References
– [1]Silva MH. Effects of low-dose chlorpyrifos on neurobehavior and potential mechanisms: A review of studies in rodents, zebrafish, and Caenorhabditis elegans. Birth Defects Res. 2020 Apr 1;112(6):445-479. |[2]Choi K, et al. Metabolism of chlorpyrifos and chlorpyrifos oxon by human hepatocytes. J Biochem Mol Toxicol. 2006;20(6):279-91. |[3]Saulsbury MD, et al. Chlorpyrifos induces oxidative stress in oligodendrocyte progenitor cells. Toxicology. 2009 May 2;259(1-2):1-9. |[4]Icenogle LM, et al. Behavioral alterations in adolescent and adult rats caused by a brief subtoxic exposure to chlorpyrifos during neurulation. Neurotoxicol Teratol. 2004 Jan-Feb;26(1):95-101.
CAS Number
– 2921-88-2
Molecular Weight
– 350.59
Compound Purity
– 99.94
SMILES
– S=P(OCC)(OCC)OC1=NC(Cl)=C(Cl)C=C1Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)|H2O : 100 mg/mL (ultrasonic)
Target
– Cholinesterase (ChE)
Isoform
– AChE
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
