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CH-223191
Price range: 90 CAD through 1,840 CAD
Products Details
Product Description
– CH-223191 is a potent and specific antagonist for the aryl hydrocarbon receptor (AhR).
Web ID
– T2448
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H19N5O
Citations
– 1. Wang K, Lv Q, Miao Y, et al. Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway. Biochemical Pharmacology. 2018 Sep;155:494-509
2. Zhang F L, Chen X W, Wang Y F, et al.Microbiota-derived tryptophan metabolites indole-3-lactic acid is associated with intestinal ischemia/reperfusion injury via positive regulation of YAP and Nrf2.Journal of Translational Medicine.2023, 21(1): 264.
References
– Kim SH, et al. Mol Pharmacol. 2006, 69(6), 1871-1878.
CAS Number
– 301326-22-7
Molecular Weight
– C19H19N5O
Compound Purity
– 0.9971
SMILES
– Cc1ccccc1N=Nc1ccc(NC(=O)c2ccnn2C)c(C)c1
Pathway
– Metabolism|||Immunology/Inflammation
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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