Download Files:
Products Details
Product Description
– Cefazolin sodium pentahydrate is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research[1]. Cefazolin sodium pentahydrate has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD)[2].
Web ID
– HY-B0756
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C14H23N8NaO9S3
References
– [1]R Quintiliani, et al. Cefazolin. Ann Intern Med. 1978 Nov;89(5 Pt 1):650-6.|[2]Peng Liang, et al. Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice. J Neuroinflammation. 2018 Aug 22;15(1):235.|[3]Barbara Å»yżyÅ„ska-Granica, et al. The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor. Sci Rep. 2020 Feb 19;10(1):2886.
CAS Number
– 115850-11-8
Molecular Weight
– 566.57
SMILES
– O=C(C(N12)=C(CSC3=NN=C(C)S3)CS[C@]2([H])[C@H](NC(CN4N=NN=C4)=O)C1=O)O[Na].O.O.O.O.O
Clinical Information
– Launched
Research Area
– Infection; Inflammation/Immunology; Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Antibiotic;Bacterial
Isoform
– β-lactam
Pathway
– Anti-infection
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
